80 research outputs found

    Participatory Irrigation Management and its Financial Viability: A Case Study

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    Water is a key input of agriculture. In the past, the area under cultivation was small and there was less stress on farmers to grow more and more of each crop. Water was considered a free good. The situation has changed since. The increase in cropping intensity has led to a rise in the demand for irrigation water. Water is not a free good any more. The provision of irrigation water to the farmer’s fields is going to be costlier. The Government of Pakistan is spending heavily on the operation and maintenance of the irrigation system yet shortage of funds is a major reason for deferred maintenance, which threatens the operational integrity of the irrigation system [World Bank (1988) and Haq (1995)]. The shortfall in O&M funding was estimated to be more than 24 percent in 1993 [World Bank (1994)]. As poor O&M has direct effect on the productivity of agriculture, indirectly it affects the whole economy [Carruthers (1981)]. The allocation of funds for the increasing O&M costs is becoming a problem for the Government of Pakistan with every successive year. One logical answer to this problem is to increase abiana1 fees from the users of irrigation water supplies. The revenue collected through abiana may be used for O&M purposes, but it has been reported that the revenue collection is far less than the expenditures incurred. Resultantly the gap has been increasing every year [Chaudhry (1989)]. This situation demands investigation of abiana recovery and increasing O&M costs to know the real situation which in turn will help in deciding whether it is feasible to divert the financing of O&M activities towards farmer organisations (completely or partially). This paper aims at estimating the present level of operation and maintenance expenditures of the H-4-R Distributary and the present situation of the abiana collection and the extent of its leakage through different means.

    Design and development from single core reconfigurable accelerators to a heterogeneous accelerator-rich platform

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    The performance of a platform is evaluated based on its ability to deal with the processing of multiple applications of different nature. In this context, the platform under evaluation can be of homogeneous, heterogeneous or of hybrid architecture. The selection of an architecture type is generally based on the set of different target applications and performance parameters, where the applications can be of serial or parallel nature. The evaluation is normally based on different performance metrics, e.g., resource/area utilization, execution time, power and energy consumption. This process can also include high-level performance metrics, e.g., Operations Per Second (OPS), OPS/Watt, OPS/Hz, Watt/Area etc. An example of architecture selection can be related to a wireless communication system where the processing of computationally-intensive signal-processing algorithms has strict execution-time constraints and in this case, a platform with special-purpose accelerators is relatively more suitable than a typical homogeneous platform. A couple of decades ago, it was expensive to plant many special-purpose accelerators on a chip as the cost per unit area was relatively higher than today. The utilization wall is also becoming a limiting factor in homogeneous multicore scaling which means that all the cores on a platform cannot be operated at their maximum frequency due to a possible thermal meltdown. In this case, some of the processing cores have to be turned-off or to be operated at very low frequencies making most of the part of the chip to stay underutilized. A possible solution lies in the use of heterogeneous multicore platforms where many application-specific cores operate at lower frequencies, therefore reducing power dissipation density and increasing other performance parameters. However, to achieve maximum flexibility in processing, a general-purpose flavor can also be introduced by adding a few Reduced Instruction-Set Computing (RISC) cores. A power class of heterogeneous multicore platforms is an accelerator-rich platform where many application-specific accelerators are loosely connected with each other for work load distribution or to execute the tasks independently. This research work spans from the design and development of three different types of template-based Coarse-Grain Reconfigurable Arrays (CGRAs), i.e., CREMA, AVATAR and SCREMA to a Heterogeneous Accelerator-Rich Platform (HARP). The accelerators generated from the three CGRAs could perform different lengths and types of Fast Fourier Transform (FFT), real and complex Matrix-Vector Multiplication (MVM) algorithms. CREMA and AVATAR were fixed CGRAs with eight and sixteen number of Processing Element (PE) columns, respectively. SCREMA could flex between four, eight, sixteen and thirty two number of PE columns. Many case studies were conducted to evaluate the performance of the reconfigurable accelerators generated from these CGRA templates. All of these CGRAs work in a processor/coprocessor model tightly integrated with a Direct Memory Access (DMA) device. Apart from these platforms, a reconfigurable Application-Specific Instruction-set Processor (rASIP) is also designed, tested for FFT execution under IEEE-802.11n timing constraints and evaluated against a processor/coprocessor model. It was designed by integrating AVATAR generated radix-(2, 4) FFT accelerator into the datapath of a RISC processor. The instruction set of the RISC processor was extended to perform additional operations related to AVATAR. As mentioned earlier, the underutilized part of the chip, now-a-days called Dark Silicon is posing many challenges for the designers. Apart from software optimizations, clock gating, dynamic voltage/frequency scaling and other high-level techniques, one way of dealing with this problem is to use many application-specific cores. In an effort to maximize the number of reconfigurable processing resources on a platform, the accelerator-rich architecture HARP was designed and evaluated in terms of different performance metrics. HARP is constructed on a Network-on-Chip (NoC) of 3x3 nodes where with every node, a CGRA of application-specific size is integrated other than the central node which is attached to a RISC processor. The RISC establishes synchronization between the nodes for data transfer and also performs the supervisory control. While using the NoC as the backbone of communication between the cores, it becomes possible for all the cores to address each other and also perform execution simultaneously and independently of each other. The performance of accelerators generated from CREMA, AVATAR and SCREMA templates were evaluated individually and also when attached to HARP's NoC nodes. The individual CGRAs show promising results in their own capacity but when integrated all together in the framework of HARP, interesting comparisons were established in terms of overall execution times, resource utilization, operating frequencies, power and energy consumption. In evaluating HARP, estimates and measurements were also made in some advanced performance metrics, e.g., in MOPS/mW and MOPS/MHz. The overall research work promotes the idea of heterogeneous accelerator-rich platform as a solution to current problems and future needs of industry and academia

    Participatory Irrigation Management and its Financial Viability: A Case Study

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    Water is a key input of agriculture. In the past, the area under cultivation was small and there was less stress on farmers to grow more and more of each crop. Water was considered a free good. The situation has changed since. The increase in cropping intensity has led to a rise in the demand for irrigation water. Water is not a free good any more. The provision of irrigation water to the farmer’s fields is going to be costlier. The Government of Pakistan is spending heavily on the operation and maintenance of the irrigation system yet shortage of funds is a major reason for deferred maintenance, which threatens the operational integrity of the irrigation system [World Bank (1988) and Haq (1995)]. The shortfall in O&M funding was estimated to be more than 24 percent in 1993 [World Bank (1994)]. As poor O&M has direct effect on the productivity of agriculture, indirectly it affects the whole economy [Carruthers (1981)]. The allocation of funds for the increasing O&M costs is becoming a problem for the Government of Pakistan with every successive year. One logical answer to this problem is to increase abiana1 fees from the users of irrigation water supplies. The revenue collected through abiana may be used for O&M purposes, but it has been reported that the revenue collection is far less than the expenditures incurred. Resultantly the gap has been increasing every year [Chaudhry (1989)]

    Estimation and separation of N-acetyl-beta-D-glucosaminidase isoenzymes in urine

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    N-acetyl-beta-D-glucosaminidase is a lysosomal enzyme made up of two isoenzymes (A and B). It has been used extensively as a marker for kidney damage. However, its estimation in urine has not been standardized. We have established a method for the estimation and separation of NAG isoenzymes by ion-exchange chromatography. In 19 experiments done so far, this method has given reproducible results. The significance of this method is that with a single experiment, one can estimate total as well as individual isoenzyme activity. Furthermore, urine constituents do not appear to interfere in this assay

    Thrombosis with thrombocytopenia syndrome after administration of AZD1222 or Ad26.COV2.S vaccine for COVID-19: A systematic review

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    Background: Cases of thrombosis with thrombocytopenia syndrome (TTS) have been reported following vaccination with AZD1222 or Ad26.COV2.S. This review aimed to explore the pathophysiology, epidemiology, diagnosis, management, and prognosis of TTS.Methods: A systematic review was conducted to identify evidence on TTS till 4th September 2021. Case reports and series reporting patient-level data were included. Descriptive statistics were reported and compared across patients with different sexes, age groups, vaccines, types of thrombosis, and outcomes.Findings: Sixty-two studies reporting 160 cases were included from 16 countries. Patients were predominantly females with a median age of 42.50 (22) years. AZD1222 was administered to 140 patients (87·5%). TTS onset occurred in a median of 9 (4) days after vaccination. Venous thrombosis was most common (61.0%). Most patients developed cerebral venous sinus thrombosis (CVST; 66.3%). CVST was significantly more common in female vs male patients (p = 0·001) and in patients aged \u3c45 years vs ≥45 years (p = 0·004). The mortality rate was 36.2%, and patients with suspected TTS, venous thrombosis, CVST, pulmonary embolism, or intraneural complications, patients not managed with non-heparin anticoagulants or IVIG, patients receiving platelet transfusions, and patients requiring intensive care unit admission, mechanical ventilation, or inpatient neurosurgery were more likely to expire than recover.Interpretation: These findings help to understand the pathophysiology of TTS while also recommending diagnostic and management approaches to improve prognosis in patients.Funding: This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors

    Pharmacognostic, phytochemical, biological and spectroscopic analyses of Capparis decidua (Forsk.) Edgew root and stem bark

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    Purpose: To investigate the pharmacognostic, phytochemical, biological and spectroscopic analyses of Capparis decidua (Forsk.) Edgew root and stem bark.Methods: Plant material (root and stem bark) was collected, authenticated, shade-dried and extracted by maceration using methanol as a solvent separately. Powder microscopy was performed using a binocular microscope. Fluorescence, physico-chemical analysis and phytochemical screening for the presence of secondary metabolites were performed using standard methods. Brine shrimp lethalitybioassay was carried out using Artemia salina bioassay, while enzymatic modulatory study was performed by α-amylase inhibition assay. Microscopic analysis was carried out with scanning electron microscopy. Spectroscopic analysis was performed by Fourier transform infrared spectroscopy (FTIR).Results: Powder microscopy showed the presence of different cellular structures. Various colors were observed under ultraviolet (UV) and ordinary light when treated with different reagents. Phytochemical screening revealed the presence of alkaloids, tannins, saponins and flavonoids but phenol and cardiac glycosides were absent from both extracts. The root bark of the plant showed significant brine shrimp lethality activity.Conclusion: Capparis decidua (Forsk.) Edgew root and stem bark contain a variety of bioactive compounds that have medicinal and therapeutic potentials. Therefore, further investigations are required to elucidate their pharmacological properties. Keywords: Capparis decidua (Forsk.) Edgew, Phytochemical, Spectroscopy, α-Amylas

    Effect of palm-sesame biodiesel fuels with alcoholic and nanoparticle additives on tribological characteristics of lubricating oil by four ball tribo-tester

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    Dilution of engine oil with unburned fuels alters its lubricity and tribological properties. In this research paper, SAE-40 lubricating oil samples were contaminated with known percentages (5%) of fuels (diesel, palm-sesame biodiesel blend (B30), B30 + ethanol, B30 + dimethyl carbonate, B30 + carbon nanotubes and, B30 + titanium oxide). The effect of all these fuels on wear and frictional characteristics of lubricating oil was determined by using a 4-ball tribo tester and wear types on worn surfaces were analyzed by using SEM. Lubricating oil diluted with B10 (commercial diesel) showed highest COF (42.95%) with severe abrasive and adhesive wear than mineral lubricant among other fuels. Lubricating oil diluted with palm-sesame biodiesel (B30 blend) with alcoholic additives showed comparatively less COF, less wear scar diameter and polishing wear due to presence of ester molecules. Lub + B30 + Eth exhibited increment in COF value (35.81%) compared to SAE-40 mineral lubricant. While lubricating oil contaminated with B30 with nanoparticles showed least frictional characteristics with abrasive wear. Lub + B30 + TiO2 showed least increment in COF value (13.78%) among all other contaminated fuels compared to SAE-40 mineral lubricant. It is concluded that nanoparticles in biodiesel blends (B30) helps in reducing degradation of lubricants than alcoholic fuel additives and commercial diesel. (C) 2021 THE AUTHORS. Published by Elsevier BV on behalf of Faculty of Engineering, Alexandria University

    Are we doing enough? Evaluation of the Polio Eradication Initiative in a district of Pakistan's Punjab province: a LQAS study

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    <p>Abstract</p> <p>Background</p> <p>The success of the Global Polio Eradication Initiative was remarkable, but four countries - Afghanistan, Pakistan, India and Nigeria - never interrupted polio transmission. Pakistan reportedly achieved all milestones except interrupting virus transmission. The aim of the study was to establish valid and reliable estimate for: routine oral polio vaccine (OPV) coverage, logistics management and the quality of monitoring systems in health facilities, NIDs OPV coverage, the quality of NIDs service delivery in static centers and mobile teams, and to ultimately provide scientific evidence for tailoring future interventions.</p> <p>Methods</p> <p>A cross-sectional study using lot quality assessment sampling was conducted in the District Nankana Sahib of Pakistan's Punjab province. Twenty primary health centers and their catchment areas were selected randomly as <it>'lots'</it>. The study involved the evaluation of 1080 children aged 12-23 months for routine OPV coverage, 20 health centers for logistics management and quality of monitoring systems, 420 households for NIDs OPV coverage, 20 static centers and 20 mobile teams for quality of NIDs service delivery. Study instruments were designed according to WHO guidelines.</p> <p>Results</p> <p>Five out of twenty lots were rejected for unacceptably low routine immunization coverage. The validity of coverage was questionable to extent that all lots were rejected. Among the 54.1% who were able to present immunization cards, only 74.0% had valid immunization. Routine coverage was significantly associated with card availability and socioeconomic factors. The main reasons for routine immunization failure were absence of a vaccinator and unawareness of need for immunization. Health workers (96.9%) were a major source of information. All of the 20 lots were rejected for poor compliance in logistics management and quality of monitoring systems. Mean compliance score and compliance percentage for logistics management were 5.4 ± 2.0 (scale 0-9) and 59.4% while those for quality of monitoring systems were 3.3 ± 1.2 (scale 0-6) and 54.2%. The 15 out of 20 lots were rejected for unacceptably low NIDs coverage by finger-mark. All of the 20 lots were rejected for poor NIDs service delivery (mean compliance score = 11.7 ± 2.1 [scale 0-16]; compliance percentage = 72.8%).</p> <p>Conclusion</p> <p>Low coverage, both routine and during NIDs, and poor quality of logistics management, monitoring systems and NIDs service delivery were highlighted as major constraints in polio eradication and these should be considered in prioritizing future strategies.</p

    Global economic burden of unmet surgical need for appendicitis

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    Background: There is a substantial gap in provision of adequate surgical care in many low-and middle-income countries. This study aimed to identify the economic burden of unmet surgical need for the common condition of appendicitis. Methods: Data on the incidence of appendicitis from 170 countries and two different approaches were used to estimate numbers of patients who do not receive surgery: as a fixed proportion of the total unmet surgical need per country (approach 1); and based on country income status (approach 2). Indirect costs with current levels of access and local quality, and those if quality were at the standards of high-income countries, were estimated. A human capital approach was applied, focusing on the economic burden resulting from premature death and absenteeism. Results: Excess mortality was 4185 per 100 000 cases of appendicitis using approach 1 and 3448 per 100 000 using approach 2. The economic burden of continuing current levels of access and local quality was US 92492millionusingapproach1and92 492 million using approach 1 and 73 141 million using approach 2. The economic burden of not providing surgical care to the standards of high-income countries was 95004millionusingapproach1and95 004 million using approach 1 and 75 666 million using approach 2. The largest share of these costs resulted from premature death (97.7 per cent) and lack of access (97.0 per cent) in contrast to lack of quality. Conclusion: For a comparatively non-complex emergency condition such as appendicitis, increasing access to care should be prioritized. Although improving quality of care should not be neglected, increasing provision of care at current standards could reduce societal costs substantially
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